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Geistlich Bio-Gide®

Geistlich Bio-Gide® is the leading collagen membrane in North America for oral tissue regeneration.1,2 It is used in combination with a bone substitute such as Geistlich Bio-Oss® or Geistlich Bio-Oss Collagen®. Geistlich Bio-Gide® integrates with surrounding tissues to protect the initial coagulum. With its unique bilayer structure, Geistlich Bio-Gide® not only prevents ingrowth of soft tissue into the augmented site, but then optimally degrades to allow for the cascade of biologic events leading to regeneration.5,6 It is the sum of these characteristics that defines the biofunctionality of Geistlich Bio-Gide® and is the basis for its long-term clinical success.

For additional information on the biofunctionality of Geistlich Bio-Gide® please review the Downloads section on the right hand side of this page.

Geistlich Bio-Gide® is naturally resorbable therefore a second surgery for removal of the membrane is not required. As it simplifies the surgical technique, and exhibits excellent wound healing properties3,4, Geistlich Bio-Gide® has fundamentally changed dental bone regeneration. 

Leading clinicians rely on Geistlich Bio-Gide® for:

  • Excellent tissue integration5,6 and undisturbed bone regeneration compared to using a bone substitute alone7,8. 
  • Native collagen structure results in fewer dehiscences compared with other available membranes3,4,9.
  • Fully resorbable, no second surgery required for membrane removal.
  • Predictable outcomes in the esthetic zone10.
  • Long-term data demonstrates predictable results in Guided Bone Regeneration (GBR) treatments when Geistlich Bio-Gide® is used in combination with Geistlich Bio-Oss®11.

Geistlich Bio-Gide® was originally developed to eliminate dehiscences and improve handling characteristics. Today, Geistlich Bio-Gide® provides the optimal requirements for bone regeneration and is the leading collagen membrane, validated by 18 years of successful clinical use in more than two million patients and documented in more than 200 scientific publications12.


  1. iData Research Inc., US Dental Bone Graft Substitutes and other Biomaterials Market, 2011.
  2. iData Inc., European Dental Bone Graft Substitutes and other Biomaterials Market, 2012.
  3. Tal H, et al.: Clin. Oral Implants Res 2008; 19: 295-302. 
  4. Zitzmann NU, et al.: Int J Oral Maxillofac Implants 1997; 12: 844-52. 
  5. Schwarz F, et al.: Clin Oral Implants Res 2006; 17: 403-09.
  6. Schwarz F, et al.: Clin Oral Implants Res 2008; 19(4): 402-15.
  7. Perelman-Karmon et al.: Int J Periodontics Restorative Dent 2013, 32(4): 459-65.
  8. Wallace SS, et al.: Int J Periodontics Restorative Dent 2005; 25(6): 551-59. 
  9. Becker J, et al.: Clin. Oral Implants Res 2009; 20(7): 742-93. 
  10. Buser D, et al.: J Periodontol 2011; 82(3): 342-49. 
  11. Jung RE, et al.: Clin Oral Implants Res. 2013; 24(10):1065-73.
  12. Pubmed September 2013. Search Term: Bio-Gide.


CAUTION: Federal law restricts these devices to sale by or on the order of a dentist or physician.