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Perio-System Combi-Pack

Geistlich Perio-System Combi-Pack combines the improved handling attributes of Geistlich Bio-Oss Collagen® 100 mg and Geistlich Bio-Gide® Perio 16 x 22 mm. Used together, they provide optimal properties for regenerative periodontal procedures.

For additional information on the benefits of Geistlich Perio-System Combi-Pack please review the Downloads section on the right hand side of this page.

User benefits

  • Proven effectiveness in regenerative periodontal therapy1-7.
  • Increased sustainable attachment level gain compared with open flap debridement alone8.
  • Easier handling and forming of Geistlich Bio-Oss Collagen® and 
Geistlich Bio-Gide® Perio simplifies periodontal treatment.
  • Long-term volume stability, bone integration and space maintenance9-15.

Geistlich Perio-System Combi-Pack is available in a convenient combination package:

  • Geistlich Bio-Gide® Perio 16 x 22 mm with sterile templates
  • Geistlich Bio-Oss Collagen® 100 mg


“Regenerative periodontal surgery in combination with Geistlich Bio- Oss Collagen® and Geistlich Bio-Gide® Perio results in markedly improved clinical and radiographic outcome.”
Dr. Beat Wallkamm, Langenthal, Switzerland


Geistlich Bio-Oss Collagen® consists of 90% Geistlich Bio-Oss® granules with the addition of 10% porcine collagen. Geistlich Bio-Oss® is scientifically proven and is the leading biomaterial in regenerative dentistry1. Combining Geistlich Bio-Oss® with highly purified porcine collagen enhances its handling characteristics making Geistlich Bio-Oss Collagen® formable and easy to handle.

Geistlich Bio-Gide® Perio is a collagen membrane possessing the same biological properties as Geistlich Bio-Gide®, with improved handling characteristics for periodontal applications. The smooth upper surface slows the absorption of moisture and allows more time for exact positioning into the defect. The firmer material facilitates trimming when dry, making it optimal for guided tissue regeneration.



  1. Cosyn J, et al.: J Clin Periodontol 2012; 39(10): 979-86.
  2. Camelo Int J Periodontics Restorative Dent 1998; 18(4): 321-31.
  3. Lundgren D, Slotte C, J Clin Periodontol 1999; 26(1): 56-62.
  4. Camargo PM, et al.: J Clin Periodontol 2000; 27(12): 889-96.
  5. Sculean A, et al.: J Clin Periodontol 2003; 30(1): 73-80.
  6. Tonetti MS, et al.: J Clin Periodontol 2004; 31(9): 770-76.
  7. Linares M, et al.: J Clin Periodontol 2006; 33(5): 351-58.
  8. Sculean A, et al.: J Clin Periodontol 2007; 34(1): 72-77.
  9. Orsini G, et al.: J Biomed Mater Res B: Appl Biomater, 2005; 74(1): 448-57.
  10. Jung RE, et al.: Clin Oral Implants Res 2013; 24(10): 1065-73.
  11. Aghaloo TL, Moy PK., Int J Oral Maxillofac Implants 2007; 22 Suppl: 49-70.
  12. Jung RE, et al.: J Clin Periodontol 2013; 40(1): 90-98.
  13. Traini T, et al.: J Periodontol 2007; 78(5): 955–61.
  14. Mordenfeld A, et al.: Clin Implant Dent Relat Res 2012, Oct 15 (Epub ahead of print).
  15. Galindo-Moreno P, et al.: Clin Implant Dent Relat Res 2012, Feb 29 (Epub ahead of print).


CAUTION: Federal law restricts these devices to sale by or on the order of a dentist or physician.