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Geistlich Fibro-Gide®

The Alternative Soft-Tissue Graft

Geistlich Fibro-Gide® is a porcine, porous, resorbable and volume-stable collagen matrix, specifically designed for soft-tissue regeneration. The matrix is made of reconstituted collagen and undergoes a chemical cross-linking method, called smart cross-linking. This process improves volume stability of the collagen while maintaining excellent biocompatibility.1-3 The porous network of Geistlich Fibro-Gide® supports angiogenesis, formation of new connective tissue and stability of the collagen network in submerged healing situations.

Geistlich Fibro-Gide® provides an alternative to the gold standard, connective tissue graft, for regenerative soft-tissue procedures.3,5,6 With Geistlich Fibro-Gide® a second surgical site is avoided and patient morbidity is reduced.3,7-9


Inspired by Nature, engineered by Geistlich

Geistlich has drawn from its vast experience in researching, analyzing and commercializing collagen-based products to produce biomaterials that are tailor-made for specific dental procedures and therapeutic solutions. Designing a preferred alternative to soft-tissue grafts has involved years of development, testing and thousands of prototypes.



  1. Instructions for Use. Geistlich Fibro-Gide®. Geistlich Pharma AG, Wolhusen, Switzerland.
  2. Thoma DS. et al. Clin Oral Implants Res. 2015 Mar; 26(3): 263–70.
  3. Thoma DS. et al. J Clin Periodontol. 2016 Oct; 43(10): 874–85.
  4. Thoma DS. et al. Clin Oral Implants Res. 2012 Dec; 23(12): 1333–9.
  5. Thoma DS. et al. Clin Oral Implants Res. 2009 Sep; 20 Suppl 4: 146–65.
  6. Thoma DS. et al. J Clin Periodontol. 2014 Apr; 41 Suppl 15: S77–91.
  7. Sanz M. et al. J Clin Periodontol 2009; 36(10): 868-76.
  8. Del Pizzo M. et al. J Clin Periodontol. 2002 Sep; 29(9): 848–54.
  9. Soileau KM. & Brannon RB. J Periodontol. 2006 Jul; 77(7): 1267–73.
  10. Zeltner M. et al. J Clin Periodontol. 2017 Apr; 44(4): 446–453.
  11. Data on file. Geistlich Pharma AG, Wolhusen, Switzerland.
  12. Dridi SM. et al. J Perio., 2008; 5(4): 231–40 (clinical).
  13. Griffin TJ. et al. J Periodontol. 2006 Dec; 77(12): 2070–9 (clinical).
  14. Cairo F. et al. J Clin Periodontol. 2012 Aug; 39(8): 760–8 (clinical).
  15. Zucchelli G. et al. J Clin Periodontol. 2010 Aug 1; 37(8): 728–38 (clinical)
  16. McGuire, M. et al. (2022). JPeriodontol. 93(3): 333-342.



CAUTION: Federal law restricts these devices to sale by or on the order of a dentist or physician.