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Soft-tissue regeneration

Soft tissue regeneration has become increasingly important in restoring functionality and esthetic appearance.

The standard materials for soft tissue regeneration are autogenous free-gingival grafts and connective tissue grafts, but harvesting soft tissues from the palate is painful, technically demanding and time-consuming.

Off-the-shelf soft-tissue products, such as Geistlich Mucograft® and Geistlich Mucograft® Seal, offer many advantages over autogeneous grafts harvested from the palate.

  • No donor site means less pain1,2, morbidity3 and surgical chair-time1,2,4.
  • Natural texture and color match to surrounding native tissue5,6.

Geistlich Mucograft® Seal is indicated for:

  • Minimally traumatic tooth extractions, when the alveolar buccal wall is preserved
  • Increasing the width of the keratinized tissue (KT) around teeth and implants

Geistlich Mucograft® and Geistlich Mucograft® Seal provide an alternative to autogenous grafts for soft-tissue regeneration1,2,4 and prevent donor site morbidity1,2.


  1. Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76.
  2. Geistlich Mucograft® Seal Advisory Board Meeting Report, 2013. Data on file, Geistlich Pharma AG, Wolhusen, Switzerland.
  3. Griffin TJ, et al.: J Periodontol 2006; 77(12): 2070-79.
  4. Lorenzo R, et al.: Clin Oral Impl Res 2012; 23(3): 316-24.
  5. Thoma DS, et al.: J Clin Periodontol 2012; 39(2): 157-65.
  6. McGuire MK & Scheyer ET: J Periodontol 2010; 81(8): 1108-17.


CAUTION: Federal law restricts these devices to sale by or on the order of a dentist or physician.

  • Why do I need keratinized tissue?
  • Should Geistlich Mucograft® be placed directly over the bone or over the periosteum?
  • Should Geistlich Mucograft® be used submerged or in open healing situations?